Abstract:ObjectiveTo investigate the clinical effect of endoscopic two-way catheterization in the treatment of anastomotic fistula after esophageal cancer surgery. MethodsFrom August 2017 to October 2020, 211 patients with postoperative anastomotic fistula of esophageal cancer treated in Zhongshan People's Hospital were selected for retrospective study. The 105 patients treated with routine intravenous nutritional support and gastrointestinal decompression were served as control group. The 106 patients placed with fistula drainage tube to the fistula mouth and three lumen nutritional tube to the jejunum under endoscopy was served as observation group. The fistula healing time, recovery eating time, hospital stays, clinical cure rate of the anastomotic fistula, nutritional status indexes(prealbumin, albumin, hemoglobin and transferrin) and the quality of life(SF-36 scale) were compared between two groups. According to CUSUM method, all cases were divided into learning improvement stage(n=60) and mastery stage(n=46), the change trend of anastomotic fistula healing time and hospital stay in the observation group with the increase of the number of surgical cases was analyzed. ResultsCompared with the control group, the fistula healing time, recovery eating time and hospital stays in the observation group were significantly reduced, and the clinical cure rate of the anastomotic fistula, SF-36 scale score and nutritional status indexes such as prealbumin, albumin, hemoglobin and transferrin were significantly increased(P＜0.01). The fistula healing time, recovery eating time and hospital stays, pain score and physical recovery score of patients in the mastery stage were significantly lower than those in the learning improvement stage(P＜0.01). ConclusionsEndoscopic two-way catheterization is safe and effective in the treatment of postoperative anastomotic fistula of esophageal cancer,60 cases can master the operation and improve the clinical curative effect.