Abstract:Objective To explore the significance of platelet aggregation function, blood viscosity and fibrinogen level in patients with acute cerebral infarction. 〖HTH〗〖STHZ〗〖HTH〗Methods〖HTSS〗〖STBZ〗〖WTBZ〗〖HTSS〗 Fifty-two patients with acute cerebral infarction admitted to Huaian Tumor Hospital from January 2020 to April 2021 were selected as the case group, and 50 healthy physical examination subjects with baseline data matching those of hospitalized patients with acute cerebral infarction in the same period were selected as the control group. The maximum aggregation rate (MAR) of platelets induced by sodium adenosine diphosphate (ADP) (ADP-MAR), the MAR induced by arachidonic acid (AA) (AA-MAR), blood viscosity (high shear rate and low shear rate), fibrinogen and some biochemical indexes in the acute phase, convalescent phase and control group were detected and compared. 〖HTH〗〖STHZ〗〖HTH〗Results〖HTSS〗〖STBZ〗〖WTBZ〗〖HTSS〗 Compared with the control group, ADP-MAR， AA-MAR and the blood viscosity test (high shear) were significantly in patients in acute phase and convalescent phase, and the increase was more obvious in patients in acute phase (P<0.05). Compared with the control group, the blood viscosity test (low shear) and fibrinogen increased in patients in the acute phase (P<0.05). In patients with acute cerebral infarction, blood viscosity test (high shear) was positively correlated with ADP-MAR, AA-MAR (r=0.458, 0.241； P<0.05), and blood viscosity at low shear rate was positively correlated with ADP-MAR, AA-MAR (r=0.122, 0.181; P<0.05). 〖HTH〗〖STHZ〗〖HTH〗Conclusion〖HTSS〗〖STBZ〗〖WTBZ〗〖HTSS〗 Combined detection of platelet aggregation rate, blood viscosity and fibrinogen can help clinicians diagnose acute cerebral infarction and predict other cardiovascular and erebrovascular diseases, suggesting that high-risk groups should take corresponding preventive measures.