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Received:September 19, 2022 Published Online:November 20, 2022
Received:September 19, 2022 Published Online:November 20, 2022
中文摘要: 目的 探讨加速康复外科联合针刺对结直肠癌术后肠道功能恢复的影响。方法选择山东青岛中西医结合医院2019年1月至2022年5月接受手术治疗的结直肠癌患者78例,其中接受ERAS干预的42例为对照组,接受ERAS+针刺治疗的36例为观察组,比较两组患者术后首次排气时间、首次排便时间、首次进食时间及住院时间;比较术前及术后5 d胃动素和胃泌素水平及术后并发症发生率。结果 观察组首次排气时间、首次排便时间短于对照组,差异有统计学意义(P<0.05)。两组术后5 d胃动素和胃泌素水平较术前降低,且观察组降低幅度低于对照组(P<0.05)。观察组总并发症发生率低于对照组,差异有统计学意义(5.56% vs 21.4%,P<0.05)。结论 加速康复外科联合针刺可以改善术后胃肠激素的分泌,加快结直肠癌术后肠道功能恢复。
Abstract:Objective To investigate the effect of acupuncture combined with enhanced recovery after surgery(ERAS) on intestinal function recovery after colorectal cancer surgery. Methods 78 patients with colorectal cancer who received surgical treatment in Shandong Qingdao Integrated Traditional and Western Medicine Hospital from January 2019 to May 2022 were selected. Among them, 42 patients who received ERAS intervention were in the control group, and 36 patients who received ERAS+ acupuncture treatment were in the observation group. The time of first exhaust, first defecation, first eating and hospitalization were compared between the two groups. The levels of motilin and gastrin before and 5 days after operation and the incidence of postoperative complications were compared. Results The first exhaust time and the first defecation time in the observation group were shorter than those in the control group, and the difference was statistically significant (P<0.05). The levels of motilin and gastrin in the two groups 5 days after operation were lower than those before operation, and those in the observation group were higher than those in the control group (P<0.05). The total complication rate in the observation group was lower than that in the control group (5.56% vs 21.4%, P<0.05).Conclusion ERAS combined with acupuncture can improve the secretion of gastrointestinal hormones and accelerate the recovery of intestinal function after colorectal cancer surgery.
keywords: Enhanced recovery after surgery Acupuncture Colorectal cancer Gastrin Motilin Complication Intestinal function
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基金项目:山东省中医药科技项目(2021Q055);青岛市2020年度中医药科研项目(2020-zyy014);青岛市2020年度医药科研指导计划(2020-WJZD092)
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