Abstract:Neoadjuvant chemotherapy (NACT) can achieve pathological complete remission in breast cancer patients with positive axillary lymph node, and sentinel lymph node biopsy (SLNB) in patients is a research hotspot of breast cancer treatment at present. However, facing the problem of high false-negative rate of SLNB after NACT, targeted lymph nodes dissection was proposed，namely，the positive lymph nodes was confirmed and localized with tissue marker clips, carbon suspension, radioactive and magnetic seeds, radar reflectors and radiofrequency identification before NACT and then removed after treatment. This paper aims to review the above-mentioned lymph node localization techniques.