Abstract:Objective To explore the value of clinical nursing pathway (CNP) combined with personalized nursing in perioperative period of patients with papillary thyroid carcinoma (PTC). Methods total of 178 patients with PTC treated in the First Affiliated Hospital of Xi'an Jiaotong University were selected and divided into control group and study group (n=89, each). The routine care was given in control group admitted to hospital from December 2019 to June 2020, and CNP combined with personalized nursing was implemented in study group admitted to hospital from July 2020 to January 2021.The hospitalization days, treatment expenses, postoperative complications, score for negative emotion and nursing satisfaction were observed in two groups. Results The hospitalization time, the treatment cost and the incidence of complications (4.49% vs 19.10%) in study group were lower than those in control group (P<0.01). After intervention, the scores of self-rating anxiety scale and self-rating depression scale in study group were significantly lower than those in control group (P<0.01). The nursing satisfaction in study group was statistically higher than that in control group (97.75% vs 85.39%, P<0.01). Conclusion In the perioperative care of PTC patients, the implementation of CNP combined with individualized nursing can reduce hospitalization time, hospital costs and the risk of complications and can effectively improve patients' anxiety and depression, with higher nursing satisfaction.