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Published Online:August 20, 2022
Published Online:August 20, 2022
中文摘要: 目的 通过对小儿散发诺如病例感染病例的症状表现、实验室检查、影像学检查等临床资料进行分析，了解其临床特征。方法 对2019年1月1日至2021年1月1日在湖北省妇幼保健院住院，诺如病毒RNA检测阳性的81例住院患儿的临床资料进性回顾性分析。结果 81例散发诺如病毒感染病例中，男41例，女40例，发病年龄均<5岁，1～3岁最高为52例（64.2%）。诺如病毒感染具有明显的季节性，武汉地区在1月及12月感染率最高。主要临床表现包括呕吐81例（100%），腹泻72例（88.9%），发热53例（65.4%），无热惊厥15例（18.5%）。以呕吐为单一首发症状的60例（74.1%）患儿，外周血白细胞明显增高，为（14.5～39.0）×10*
Abstract:Objective To understand the clinical characteristics of sporadic norovirus cases in children by analyzing the clinical data such as symptoms, laboratory examination and imaging examination. Methods The clinical data of 81 hospitalized children with norovirus RNA positive in Hubei Maternal and Child Health Hospital from January 1, 2019 to January 1, 2021 were analyzed retrospectively. Results Among 81 cases of sporadic norovirus infection, there were 41 males and 40 females. The age of onset was less than 5 years old, and the highest age was 52 cases（64.2%） from 1 to 3 years old. Norovirus infection had obvious seasonality, and the infection rate in Wuhan was the highest in January and December. The main clinical manifestations included vomiting [100%(81/81)], diarrhea [88.9%(72/81)], fever [65.4%(53/81)] and febrile convulsion [18.5%(15/81)]. In 60 children（74.1%） with vomiting as the single first symptom, the peripheral blood leukocytes increased significantly（14.5-39.0）×10*
文章编号： 中图分类号：R725.1 文献标志码：B
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