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Published Online:August 20, 2022
Published Online:August 20, 2022
中文摘要: 目的 〖JP2〗研究睡眠障碍与SYNTAX评分的相关性，了解心内科患者睡眠障碍现况及影响因素。方法 纳入2015年7月至2016年1月于哈尔滨医科大学附属第一医院心内科行冠状动脉造影术的连续病例233例。术前行匹兹堡睡眠质量指数问卷（PSQI）调查，依据问卷得分分为睡眠障碍组（PSQI＞7分）和非睡眠障碍组（PSQI≤7分）。计算SYNTAX评分对冠脉病变严重程度分组低危组(0～22分)、中危组(＞22～32分)及高危组(＞32分)。并记录冠状动脉性心脏病（CHD）危险因素如既往史、生化系列、心脏彩超等，分析睡眠障碍与SYNTAX评分的相关性。结果 两组年龄、BMI、职业、文化程度、吸烟史、饮酒史、高血压史、糖尿病史、总胆固醇、三酰甘油、低密度脂蛋白胆固醇、脂蛋白a、空腹血糖、尿素氮、肌酐、丙氨酸氨基转移酶（ALT）、天门冬氨酸氨基转移酶（AST）等差异无统计学意义（P＞0.05）。睡眠障碍组女性比例高于非睡眠障碍组，差异有统计学意义（P＜0.01）。两组心脏彩超主动脉瓣环内径、左心房前后径（LAD）、左心室舒张末期内径（LVDd）差异有统计学意义 （P＜0.05）。非睡眠障碍组冠脉病变严重程度轻于睡眠障碍组，差异有统计学意义（P＜0.01）。多因素logistic回归分析结果显示，女性患者出现睡眠障碍是男性患者的2.51倍；中危组患者出现睡眠障碍的可能性是低危组的3.29倍，高危组患者出现睡眠障碍的可能性是低危组的7.68倍。结论 睡眠障碍与冠状动脉病变SYNTAX评分呈正相关。
中文关键词: 睡眠障碍 冠状动脉性心脏病 匹兹堡睡眠质量调查量表 SYNTAX评分
Abstract:Objective To study the relationship between sleep disorder and SYNTAX score to explore the status and influencing factors of sleep-disorder in patients with cardiovascular disease. Methods A total of 233 consecutive patients undergoing coronary angiography in the First Affiliated Hospital of Harbin Medical University from July 2015 to January 2016 were included. According to the preoperative Pittsburgh sleep quality index (PSQI) questionnaire, the patients were divided into sleep disorder group (PSQI>7 points) and non-sleep disorder group (PSQI≤7 points). The SYNTAX score was calculated, and the risk factors of coronary heart disease, such as previous history, biochemical parameters, and color Doppler echocardiography were observed to analyze the correlation between sleep-disorder and SYNTAX score. Results There was no significant difference in age, BMI, occupation, education level, smoking, drinking, hypertension, diabetes and levels of total cholesterol, triglyceride, low density lipoprotein cholesterol, lipoprotein a, fasting blood glucose, urea nitrogen, creatinine, ALT, AST and other indicators between two groups (P>0.05).The female patients were more prone to having sleep disorders than male patients (P<0.01). There were significant differences in the inner diameter of the aortic valve annulus, left atrial anteroposterior diameter (LAD), and left ventricular end-diastolic diameter (LVDd) between the two groups （P＜0.05）. The severity of coronary artery disease in the non-sleep disorder group was lighter than that in the sleep disorder group, and the difference was statistically significant (P<0.01). Multivariate logistic regression analysis showed that the prevalence of sleep disorders in female patients was 2.51 times higher than that in male patients. The probability of sleep disorder in the middle-risk group was 3.29 times higher than that in the low-risk group, and that in the high-risk group was 7.68 times higher than that in the low-risk group. Conclusion Sleep disorders is positively correlated with SYNTAX score.
文章编号： 中图分类号：R541.4 文献标志码：A
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