Abstract:Objective To evaluate the safety of CT-guided microwave ablation in the treatment of pulmonary nodules and the short-term curative effects at 6 months after operation. Methods Twelve patients receiving microwave ablation for pulmonary nodules in the Affiliated Hospital of Beihua University from November 2020 to May 2021 were analyzed retrospectively. The postoperative complications were observed, and the local curative effects of pulmonary nodules lesions were evaluated by chest CT at 1-, 3- and 6-month after operation. Results The microwave ablation was successfully performed in all 12 patients. There were 3 cases of postoperative pneumothorax, 1 case of hemoptysis and 1 case of pleural effusion. One patient was lost to follow-up 6 months after operation. The nodular lesions were completely ablated in 11 patients, manifested as focal fibrosis, solid nodule size reduction and local cavity formation. No recurrent lesions were found at 6 months after operation. Conclusion In the treatment of pulmonary nodules, CT-guided percutaneous microwave ablation has definite short-term clinical efficacy with less complications, and can be used as a supplementary means for the patients who cannot tolerate surgery or are unwilling to accept surgery.