Abstract:Objective To evaluate and summarize the best evidence for the management of prediabetes. Methods All evidences on prediabetes management in Up-To-Date, Cochrane Library, Medline, PubMed, China Biomedical Literature Database, Wanfang, CNKI, Yimaitong and other databases in recent 10 years were searched by computer, including guidelines, expert consensus, evidence summary and systematic evaluation, etc. By JBI Evidence Pre-Grading and Evidence Recommendation Grading System (2014), the level of evidence and the strength of recommendation were classified. Results A total of 8 literatures were included, including 3 guidelines, 3 expert consensuses and 2 systematic reviews. Finally, 15 pieces of best evidence were summarized, covering 7 aspects of evaluation, health education, lifestyle intervention, monitoring, drug intervention, traditional Chinese medicine intervention and psychological intervention. Conclusion In the management of prediabetes, the best evidence should be selected in combination with the clinical situation and the promoting and hindering factors of the applied evidence, so as to form a more scientific and evidence-based management plan.