Abstract:ObjectiveTo construct a perioperative pain management plan for laparoscopic cholecystectomy (LC), and analyze its application effect. Methods A perioperative pain management plan for LC was developed through literature research method, questionnaire survey and Delphi method. Using purpose sampling method, 58 patients treated with LC in People's Hospital of Zhenhai District, Ningbo between July 2019 and December 2019 were selected as the control group, and were given routine pain nursing. 45 patients treated with LC between January 2020 and June 2020 were selected as the observation group, and were given perioperative pain management. The postoperative pain scores, additional use of analgesics and satisfaction with pain control were compared between the two groups. Results The resting pain scores at different time points after operation and active pain score within 24 hours after operation of the observation grouPwere lower than those of the control grouP(P<0.05). The rate of additional use of analgesics in the observation grouPin 7-12 hours after operation was lower than that in the control grouP(P<0.05). The score for satisfaction with postoperative pain control of the observation grouPwas higher than that of the control grouP(P<0.05). Conclusions The perioperative pain management plan for LC can alleviate postoperative pain of the patients, reduce additional use of analgesics after operation, and improve the patients' satisfaction with pain control.