Abstract:Objective Through a survey of the nurses in the fever clinic in level-A tertiary hospital, to understand the acute stress disorder （ASD） of the nurses in the fever clinic of the patients with COVID-19 infection and suspected infection,and to analyze the influencing factors. Methods From January 1, 2019 to January 1, 2021, the fever clinic nurses in four designated hospitals for COVID-19 in Haikou City, Hainan Province were selected as the research objects. General information questionnaire, Stanford acute stress response questionnaire (SASRQ), Connor Davidson resilience scale and simple coping style scale were used to investigate 217 nurses in fever clinic. Results The total score of SASRQ was 36.71±20.27.In the univariate factor analysis, age, marital status, fertility, education and working years were statistically significant among different ASD groups (P＜0.01，P＜0.05). Spearman correlation analysis showed that psychological resilience and each dimension were negatively correlated with the total score and each dimension of SASRQ (P＜0.05), negative coping was positively correlated with the total score and each dimension of SASRQ (P＜0.01), and positive coping was negatively correlated with most of the total score and each dimension of SASRQ (P＜0.05, P＜0.01). Conclusion Fever outpatient nurses have obvious acute stress response symptoms, which are related to the level of resilience and negative coping styles.