Abstract:Objective To investigate the effect of entering the seminal vesicle through the opening of ejaculatory duct of normal anatomical structure and breaking the wall of prostatic vesicle in the treatment of seminal vesiculitis. Methods A total of 215 patients with chronic seminal vesiculitis with hematospermia as the main manifestation treated in Xuzhou Central Hospital from January 2012 to October 2020 were included. They were divided into normal ejaculatory duct opening entry group (group A, n=82) and prostate vesicle wall breaking entry group (group B, n=133). The patients were followed up for at least 6 months to observe the recurrence 6 months after operation, the number of red blood cells in semen 1 month after operation, the volume of seminal vesicle under color Doppler ultrasound, and the incidence of ejaculatory pain 1 month after operation. Results All patients completed the operation. The postoperative recurrence rate in group A was significantly higher than that in group B (12.20% vs 4.51%, P<0.05). One month after operation, the number of red blood cells and seminal vesicle volume in group B were better than those in group A, and the incidence of ejaculatory pain in group B was lower than that in group A (P<0.05,P<0.01). Conclusion For patients with chronic seminal vesiculitis, seminal vesiculoscopy and treatment by breaking the wall of prostate vesicle into seminal vesicle has lower postoperative recurrence rate and better treatment effect.