Abstract:Objective To analyze the effect of neuroendoscopic minimally invasive surgery on cerebral oxygen metabolism and prognosis in patients with basal ganglia hemorrhage （BGH）.Methods A total of 120 patients with BGH diagnosed and treated from November 2019 to March 2021 in Gezhouba Central Hospital of Sinopharm were selected and divided into two groups, 60 patients in the endoscopy group underwent neuroendoscopic surgery; 60 patients in the craniotomy group underwent craniotomy. The cerebral oxygen metabolism, neurological function and prognosis of the two groups were compared. Results The operation time, intraoperative blood loss, ICU stay and hospital stay in endoscopic group were shorter than those in craniotomy group (P<0.01). Compared with craniotomy group, the residual amount of hematoma was lower, and the hematoma clearance rate was higher in endoscopic group (P<0.01). After operation, the scores of the NIHSS scale and GCS scale of the two groups decreased, and the scores of the endoscopy group were lower than those of the craniotomy group (P<0.01). The cerebral oxygen metabolism of the two groups was improved at 1 week after operation, and the metabolic improvement of the endoscopic group was higher than that of the craniotomy group (P<0.01). The prognosis good rate of the endoscopic group was higher than that of the craniotomy group at 3 months after surgery (80.00% vs 60.00%, χ²=5.714, P=0.017). The incidence of complications in the endoscopic group was lower than that in the craniotomy group within 3 weeks after surgery (3.33% vs 16.67%, χ²=5.926, P=0.015).Conclusion Neuroendoscopic surgery can improve the hematoma clearance rate of patients with BGH, the cerebral oxygen metabolism recovers significantly, and the prognosis is good.