Abstract:Objective To explore the effect and safety of coronary rotational atherectomy(CRA) in patients with non-ST segment elevation acute coronary syndrome(NSTE-ACS) undergoing percutaneous coronary intervention (PCI) and its influence on calcification. Methods A retrospective analysis was performed on the clinical data of 83 patients with NSTE-ACS received PCI from July 2019 to September 2020.The patients were divided into observation group (n=19) and control group (n=64) according to whether CRA was conducted.The immediate Results of operation,the incidence of intraoperative complications,and the main adverse cardiovascular events (MACE) and complications during 3-month follow-up were compared between two groups. Results Compared with those in control group,the minimum cross-sectional area of stent［(7.54±0.51)mm^2- vs(5.78±0.76)mm^2-］,the proportion of residual stenosis <20%(94.73% vs 68.75%) and operation time ［(164.00±22.00)min vs (96.00±27.00)min］ significantly increased in observation group (P<0.05,P<0.01).There were no significant differences in the incidences of intraoperative complications and MACE within 3 months between two groups(P>0.05). Conclusion CRA can improve the immediate effect of PCI in NSTE-ACS patients without increasing the incidences of intraoperative complications and MACE.