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Received:August 20, 2020 Published Online:May 20, 2021
Received:August 20, 2020 Published Online:May 20, 2021
中文摘要: 目的 分析腹腔镜袖状胃切除联合食管裂孔疝修补术(LSG+HHR)对肥胖合并胃食管反流病(GERD)患者的短期治疗效果。方法 回顾性分析2019年3月至 2020年5月在新疆维吾尔自治区人民医院接受LSG+HHR治疗的43 例肥胖合并GERD 患者的临床资料,收集患者术前及术后6个月的胃食管反流病调查问卷(GERD-Q)评分、测酸、测压等相关临床资料。结果 患者术后6个月体重、BMI与术前相比降低,差异有统计学意义(P<0.05);减重疗效评估效果极佳11例,效果良好23例,有效7例,疗效失败2例,有效率为95.3%。与术前相比,术后Gerd-Q 评分显著降低(7.15±0.83 vs 9.84±1.37,t=11.277,P<0.01)。通过对24 h食管pH进行监测,发现患者酸反流(pH值≤4)次数、弱酸反流(4
Abstract:Objective To investigate the short-term therapeutic effect of laparoscopic sleeve gastrectomy(LSG) combined with hiatal hernia repair(HHR) in obese patients with gastroesophageal reflux disease (GERD).Methods The clinical data of 43 obese patients with GERD undergoing LSG+HHR in Xinjiang Uygur Autonomous Region People′s Hospital from March 2019 to May 2020 were retrospectively analyzed.GERD-Questionnaire (GERD-Q),acid measurement and high resolution manometry (HRM) were collected before and 6 months after operation.Results The weight and BMI of the patients at 6 months after operation were lower than those before the operation,and the difference was statistically significant (P<0.05 );in weight loss evaluation,11 cases were excellent,23 cases were effective,7 cases were effective,2 cases were efficacy failure,and the effective rate was 95.3%.Compared with that before operation,GERD-Q score decreased significantly after operation (7.15±0.83 vs9.84±1.37,t=11.277,P<0.01 ).Esophageal 24 h pH monitoring showed that the times of acid reflux (pH≤4) and weak acid reflux (4Conclusion In the treatment of obesity complicated with GERD,LSG with HHR is effective and can achieve the dual purpose of anti- reflux and weight-loss,so as to prevent the occurrence and development of GERD.
keywords: Obesity Gastroesophageal reflux disease Laparoscopic sleeve gastrectomy Hiatal hernia repair
文章编号: 中图分类号:R656.6+1 R655.4 文献标志码:B
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