Abstract:Objective To analyze the correlations between lipid secretions in mammary duct and clinical features of non-puerperal mastitis (NPM).Methods A retrospective analysis was performed in 232 NPM patients cured after undergoing surgery with complete medical history in Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine from January 2010 to December 2014.Spearman rank correlation analysis was used to explore the associations of intraductal lipoid secretion with general information,clinical characteristics,laboratory indicators and post-treatment recurrence of NPM patients.Results In 232 cases of NPM,93 (40.09%) were scored as 0 (no secretion),60 (25.86%) were scored as 2 (less secretion),55 (23.71%) were scored as 4 (medium secretion) and 24 (10.34%) were scored as 6 (more secretion).There were significant differences in the number of births,the time from the last birth to the onset of NPM,breast mass,breast skin redness,breast pain,white blood cell count (WBC),neutrophil (NC),hospitalization time and recovery time in patients with different secretion scores ( P<0.05, P<0.01),however,there were no significant differences in age,body mass index,lactation time,breast abscess,serum prolactin (PRL),wound healing time and recurrence rate ( P>0.05).Spearman rank correlation analysis showed that lipid secretion in mammary duct was positively correlated with the number of births,breast mass,breast skin redness,breast pain,WBC and NC,hospital stay and recovery time ( P<0.05) and was negatively correlated with the time from last birth to onset ( P<0.01).Conclusion Lipoid secretions in mammary duct can induce NPM,aggravate local symptoms and prolong treatment time.