Abstract:Objective To analyze the survival prognostic factors of pneumonia caused by human infected H7N9,H1N1 and H3 avian influenza virus through chest CT feature. Methods The general data and chest CT images of 5 cases of H7N9,8 cases of H1N1 and 3 cases of H3 pneumonia admitted to the Third Affiliated Hospital of Soochow University from December 2016 to May 2018 were reviewed,and the influencing factors of survival and prognosis were analyzed. Results Among 16 cases of avian influenza pneumonia,6 cases died,including 4 cases of H7N9 and 2 cases of H1N1.Compared with the survival group,the consolidation (P=0.007) and air bronchogram (P=0.035) of chest CT were more likely to appear in death group.The age of death group was little younger than that of survival group without significant difference ［(48.17±8.93) years old vs (60.80±13.51)years old,t=2.025,P=0.062］.Death occurred more in H7N9 group,but the difference was not significant (P=0.076).Avian influenza virus was more likely to affect bilateral lower lungs,especially in right side.Compared with the survival group,the area of lung lesions involved in the death group was more extensive,including the whole lung,right lung,right upper lung,right lower lung,left lung and left upper lung(P<0.05,P<0.01).The death group was more likely to involve the apex of the right lung,the right anterior segment,the medial segment of the right middle lobe,the dorsal segment of the right lower lung,the posterior basal segment of the right lung,the upper lingual segment of the left lung,and the lower lingual segment of the left lung and posterior basal segment of the left lung(P<0.05,P<0.01).There was no significant difference in gender,ground glass opacity,nodules,interlobular septal thickening,grid shadow,pleural effusion and lymph node enlargement between the two groups (all P>0.05). ConclusionsCompared with the survivors,the patients who died from avian influenza pneumonia were slghtly younger in onset age,and occurred in H7N9 a little more.The chest lesions in the death group were prone to consolidation and air bronchogram,and the lesions involved a wide range.CT examination is helpful to more accurately evaluate the condition and prognosis of patients with avian influenza pneumonia,and then guide the treatment.