Abstract:Objective To investigate the clinical characteristics and follow-up status of patients with primary gout based on chronic disease management. Methods A retrospective cohort study was made on 383 patients with primary gout who were enrolled in database in chronic disease management from January 2015 to June 2017.The baseline characteristics and treatment responses of the patients were analyzed, and the follow-up evaluations were carried out at 1-, 3-, 6-and 12- month after treatment in the specialist department.The further consultation rate, standard rate of serum uric acid and the related factors influencing the standard treatment of blood uric acid were observed and analyzed. Results The ratio of male to female patients was 8.46[DK]∶1, the age was (55.21±16.04) years old, mean BMI was (15.47±2.40)kg/m² and the incidence of primary gout was higher in the patients of 41-55 years old (31.85%).There were 59 patients with gout stone (15.40%) and 83 patients with gouty nephropathy (21.17%), who were prone to have cardivascular disease.The recurrence rate of primary gout was 59.53% at 3 month, 32.90% at 6 month and 10.7% at 1 year after treatment.In 6 months, there were 72 cases with normal blood uric acid level (serum urate≤360 μmol/L, standard group) and 54 cases without reaching the normal level (serum urate>360 μmol/L, non-standard group).Univariate analysis showed that there were no significant differences in age, BMI, course of disease, medical history of hypertension, diabetes, hyperlipidemia, kidney stones and coronary heart disease between two groups (all P>0.05), but there were statistical differences in gender, VAS score, incidences of gout nephropathy and gout stone and use of uric acid lowering drugs (all P<0.05).Multiple Logistic regression analysis indicated that gouty nephropathy, use of urate-lowering drugs and gouty tophus were the main factors affecting the blood uric acid level of patients with primary gout(all P<0.01). Conclusion Under chronic disease management in Mianyang area, the follow-up rate and the standard-reach rate of blood uric acid level are relatively low in patients with primary gout.It is necessary to strengthen the education for normal blood uric acid level and develop the patient-centered care of chronic disease management.