Abstract:ObjectiveTo explore the effect and mechanism of autologous arteriovenous fistula (AVF) on patients′ cardiac function and blood pressure.MethodsEighty-three patients undergoing AVF angioplasty and long-term maintenance hemodialysis from January 2016 to June 2017 were selected as the research subjects.All the patients were followed up for 2 years.Before angioplasty and at 1-,3-,6-,12-,24- month after dialysis,the cardiac function and blood pressure levels were measured respectively,and their changes were compared before and after dialysis.ResultsThere were significant differences in cardiac index (CI),cardiac output (CO),left ventricular end diastolic volume (LVEDV),left ventricular diameter (LVD),left atrial diameter (LAD),right ventricular diameter (RVD),ejection fraction (EF),systolic and diastolic blood pressure levels before operation and after hemodialysis (P<0.05).CI and CO showed an upward trend at 1,3,6,and 12 months after dialysis,and decreased at 24 months after dialysis; EF showed a upward trend at 1,3,and 6 months after dialysis,and showed a downward trend at 12,24 months after dialysis; LVEDV,LVD,LAD,RVD showed an upward trend at 1,3,6,12,and 24 months after dialysis.The systolic blood pressure level within 12 months after dialysis was significantly higher than that before operation(P<0.05) and was significantly lower at 24 months after dialysis than that before operation (P<0.05).Diastolic blood pressure was lower at 1,3,6,12,and 24 months after dialysis than before operation(P<0.05),but there was no significant change during 1,3,6,and 12 months after dialysis,and showed a downward trend at 24 months after dialysis.ConclusionThe application of autogenous arteriovenous fistula affects the hemodynamics of patients,which can lead to the early compensatory enhancement of cardiac function and the increase of systolic blood pressure.However,the cardiac function and the systolic pressure decrease,and the diastolic blood pressure remains at a low level during cardiac decompensation.