Abstract:Objective To investigate the advantages and clinical value of enhanced recovery after surgery (ERAS) in peri-operative management of early-stage non-small cell lung cancer (NSCLC) after radial operation. Methods The clinical data of 98 patients with early-stage NSCLC receivied surgical treatment from January 2017 to May 2019 were collected.The patients with ERAS concept in the perioperative management were designed in ERAS group (n=49),and the patients with traditional perioperative concept were taken as control group (n=49).Preoperative general data and relevant clinical indicators were compared between two groups. Results There were no significant differences in the patient′s general data,operative time,number of resected lymph nodes,intraoperative blood loss,time of closed drainage tube removal,postoperative drainage volume and complications between two groups (all P>0.05).Numerical rating scale (NRS) scores at postoperative 24 h (2.6±0.6 vs 4.2±0.8),48 h (1.4±0.5 vs 3.3±0.6) and 72 h(0.9±0.4 vs 1.9±0.5),time of drainage tube removal［(2.5±0.5)d vs(3.0±0.5)d］ and postoperative hospital stay［(6.0±1.5)d vs(7.5±3.0)d］ in ERAS group were significantly lower than those in control group (all P<0.01).All patients were followed up for 1-3 months,and no death occurred in perioperative period.There were no re-hospitalized or re-operated cases due to complications within 1 month after discharge. Conclusion It is safe and effective to apply ERAS concept in perioperative management of early-stage NSCLC patients receiving radial operation and can accelerate the postoperative recovery of patients.