Abstract:Objecitve To investigate the safety and clinical value of laparoscopic splenectomy combined with pericardial devascularization and laparotomy in the treatment of patients over 70 years old with cirrhosis and portal hypertension. Methods The clinical data of 58 elderly patients over 70 years old admitted to Huai′an No.1 Hospital Affiliated to Nanjing Medical University from June 2010 to June 2019 were analyzed retrospectively.According to the different operation methods, they were divided into two groups. Among them, the laparoscopy group (26 cases) received laparoscopic splenectomy combined with pericardial devascularization, and the laparotomy group (32 cases) performed laparotomy postoperative condition. Results There was no significant difference in the operation time, intraoperative bleeding volume, blood transfusion ratio, hospitalization cost and 30 day readmission ratio between the laparoscopy group and the laparotomy group (P>0.05), but in the total incidence of postoperative complications, postoperative hospitalization time, pain score, postoperative anal exhaust time and other indicators, the laparoscopy group was significantly lower than the laparotomy group (P<0.05). Conclusion Laparoscopic splenectomy combined with pericardial devascularization is safe and feasible in the elderly over 70 years old, and its short-term effect is better than that of laparotomy, which is worthy of clinical promotion.