Abstract:Objecitve To investigate the effect of arthroscopy combined with biplane open osteotomy on the score and satisfaction of Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index in patients with medial compartment osteoarthritis. Methods A total of 82 patients with medial interventricular osteoarthritis who received treatment in Chifeng Municipal Hospital from February 2016 to February 2019 were selected and divided into control group and observation group randomly (n=41, each). The control group was treated with conventional proximal tibial osteotomy, and the observation group was treated with arthroscopy and biplane osteotomy.The time of hospitalization, healing time of osteotomy area, incidence of postoperative complications, satisfaction and the levels of serum matrix metalloproteinase-1 and MMP-3 were compared between the two groups. The patients were followed up for 6 months, and the medial angle of proximal tibia, flexion of knee joint, WOMAC score and Lysholm knee joint score were compared between the two groups. Results The hospitalization time of the observation group [(9.52±1.84)d vs (10.85±1.63)d], the healing time of the osteotomy area [(6.02±0.87)months vs (6.94±1.02)months] were shorter than that of the control group (P<0.01).On the 3rd and 7th day after operation, the levels of MMP-1 and MMP-3 in the two groups were lower than those before operation, and the level of MMP-1 and MMP-3 in the observation group was lower than that in the control group (P<0.05, P<0.01).At 3 and 6 months after operation, the flexion of medial angle of proximal tibia and knee joint in the two groups increased compared with that before operation(P<0.05), but there was no significant difference between the two groups (P>0.05). At 3 and 6 months after operation, Lysholm and WOMAC scores of the two groups were significantly improved compared with those before operation(P<0.05).Lysholm score of the observation group was higher than that of the control group, and WOMAC score was lower than that of the control group(P<0.05，P<0.01).There was no significant difference in postoperative complications and satisfaction between the observation group and the control group (P>0.05). Conclusion Arthroscopy combined with biplane open osteotomy of the proximal tibia can correct the deformity, improve the joint function, reduce the level of serum MMPs, help the patients recover after operation, and improve the patients′ satisfaction after operation.