Abstract:Objective To study clinical application of anti Mullerian hormone (AMH) in evaluating ovarian reserve function after laparoscopic endometriosis cysts surgery. Methods A total of 73 patients with endometriotic cyst treated by laparoscopic surgery from May 2017 to August 2018 were selected as the subjects, in whom the levels of AMH, follicle stimulating hormone (FSH), luteinizing hormone(LH), FSH/LH ratio and estrogen (E2) were measured by radioimmunoassay before operation, 1 and 6 months after operation. Comparison of AMH was made in patients with single and bilateral ovarian endometriosis cyst and with different diameter of endometriosis cyst before and after operation. Results At one month after operation, the levels of serum FSH, LH, E2 and FSH/LH were statistically higher than those before and 6 months after operation (all P<0.05), but there were no significant differences in them between pre-operation and postoperative 6-month (all P>0.05). From preoperative, postoperative one month to six months after operation, the level of AMH decreased gradually with statistical difference (P<0.01). Before and 1 month after operation, there were no significant differences in AMH between patients with single or bilateral ovarian endometriosis cyst and those with endometriosis cyst diameter ≥ 4 cm or<4 cm. At six months after operation, AMH level in patients with single endometriosis cysts was significantly higher than that in patients with bilateral endometriosis cysts, and it in patients with endometriosis cyst diameter more than 4 cm was significantly lower than that in patients with endometriosis cysts diameter less than 4 cm (P<0.05, P<0.01). Conclusion Laparoscopic endometriosis cysts surgery can lead to decreased ovarian reserve function after operation. AMH is more sensitive than other sex hormones in reflecting ovarian reserve function and can be used as a reference index to evaluate ovarian reserve function after laparoscopic endometriosis cysts.