Abstract:Objective To explore the distribution and drug sensitivity of pathogenic bacteria in diabetic foot ulcer infection to provide basis for the correct selection of clinical antimicrobial treatment. Methods The clinical data of 95 patients with diabetic foot ulcer attending hospital from January 2017 to December 2018 was collected,and the descriptive analysis was made on the results of pathogen culture and drug sensitivity test from foot ulcer secretion. Results There were 77 strains of bacteria from the secretions of 95 patients,including 43 strains (55.8%) gram positive bacteria(G⁺),30 strains(39.0%)gram negative bacteria (G^-) and 4 strains (5.2%) of fungi.G⁺bacteria were mainly staphylococcus aureus,enterococcus faecalis and staphylococcus haemolyticus;G^- bacteria were mainly escherichia coli,enterobacter cloacae and pseudomonas aeruginosa.The top three bacteria were staphylococcus aureus,escherichia coli and enterobacter cloacae,accounting for 58.4% of the total bacteria strains.Drug sensitivity testing showed that the main G⁺bacteria were sensitive to vancomycin,teicoplanin,rifampicin and linezolid,while the main G^-bacteria were highly sensitive to meropenem,imipenem,piperacillin sulbactam and cefoxitin. Conclusions The pathogens of diabetic foot ulcer infection are mainly G⁺ bacteria.Therefore,antibacterial drugs can be used for staphylococcus aureus,escherichia coli and enterobacter cloacae before the pathogenic bacteria are identified and can be adjusted after the pathogenic bacteria are determined so as to use antibacterial drugs in the early stage correctly,control infection actively and improve prognosis.