Abstract:Objective To explore the correlation between two-dimensional echocardiography (2D-UCG) and B-type brain natriuretic peptide(BNP),6-minute walking test(6MWT),dyspnea scale ［modified Medical Research Council (mMRC)］ in evaluating right ventricular dysfunction in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD). Methods A total of 249 patients with clinically confirmed AECOPD treated in Emergency Department from May 2016 to May 2018 were selected.General data were collected,and BNP,6MWT,mMRC and 2D-UCG were measured for all patients.The diagnostic accuracy and Pearson correlation analysis were used to evaluate the diagnostic efficacy The diagnostic coincidence rate and Pearson correlation method were used to analyze the diagnostic efficacy and correlation of 2D-UCG with BNP, 6MWT, and MMRC for the evaluation of right ventricular dysfunction in patients with AECPD. Results The risk of right ventricular insufficiency in 249 patients was judged by any one of the four test results of 2D-UCG, 94 (37.8%) were positive,and 155 (62.2%) were negative.Compared with BNP, 6MWT and MMRC in the diagnosis of right ventricular insufficiency in AECOPD patients,the coincidence rates of 2D-UCG were 67.87%, 42.57% and 54.22% respectively, and there was a positive correlation between two-dimensional echocardiography and BNP, 6MWT and mMRC (r=0.534,0.605,0.571,all P<0.01). Conclusions The incidence of right ventricular insufficiency in AECOPD patients is higher.2D-UCG is significantly correlated with BNP,6WMT and mMRC in evaluating the risk of right ventricular insufficiency in AECOPD patients.It suggests that 2D-UCG can evaluate the right ventricular function in COPD patients effectively and can complement each other with BNP,6WMT and mMRC in the risk assessment of right ventricular dysfunction in AECOPD.