Abstract:Objective To investigate the diagnostic value of superb micro-vascular imaging (SMI) in pannus of rheumatoid arthritis. Methods A total of 50 patients with RA who received treatment in Chengde Central Hospital from December 2016 to October 2018 were selected and examined by SMI and Doppler flow imaging (PDI).The synovium thickness and blood flow signals of all patients were measured,and the blood flow signals were graded.The patients were instructed to take leflunomide and methotrexate orally,and hormone and non-steroidal anti-inflammatory drugs (3 months in total) were given according to their condition and body condition cure.The correlation between DAS28 score of RA patients and SMI blood flow signal grade was statistically analyzed,and the related indexes ［anticoagulant peptide (CCP),rheumatoid factor (RF),C-reactive protein (CRP),erythrocyte sedimentation rate (ESR),synovium thickness］ were compared before and after the treatment. Results In this group,the synovium of 50 RA patients was thickened 80 joints,the blood flow signal display rate of SMI was higher than that of PDI (86.25% vs 63.75%,P<0.01).There was significant difference in the grade of bload flow signals between SMI and PDI (P<0.01).Spearman test showed that there was a significant positive correlation between SMI blood flow signal grading and DAS28 score (r=0.818,P<0.01).After the treatment,the levels of anti CCP antibody,RF,CRP and ESR decreased,and the synovial thickness decreased (P<0.01). ConclusionSMI can effectively evaluate the condition of hyperplastic synovium and pannus in RA patients,which has a significant positive correlation with the activity of RA lesions,and can evaluate the disease treatment,which can provide an objective reference for the evaluation of activity and severity of RA lesions and treatment effect.