Abstract:Objective To discuss the treatment of complex and multi-segment fracture of tibia and fibula, and to analyze the effect of interlocking intramedullary nail assisted with small plate technique in the treatment. Methods A total of interlocking intramedullary nail combined with plate internal fixation for treatment of 27 cases of multiple tibiofibular fractures were collected from May 2011 to May 2018.The post-operative effect, complication and function were observed after the treatment. Results A total of 27 patients were followed, the followed time was 6 to 23 months, 13.1 months on average.Intra-operation bleeding loss was 210 to 230 (230±20) ml, and operation time was 50 to 110 (80±10) min.All incisions healed in one stage without skin infection or necrosis.Bone healing was achieved at the fracture ends.The healing time ranged from 12 to 34 weeks (18.56±1.74).According to Johner-Wruhs scoring criteria, 22 cases were excellent (81.48%), 4 cases were good (14.81%), 1 case was fair (3.71%) and 0 cases were poor.No delayed union, nonunion and malunion were observed.No failure, loosening or rupture of internal fixation occurred during follow-up. Conclusion Interlocking intramedullary nail combined with reconstruction plate can shorten the operation time and reduce the amount of bleeding, so as to effectively reduce wound infection and skin necrosis, which is conducive to fracture healing.