Abstract:Objective To investigate the clinical effect and application of autologous free fat graft for repair of tear trough deformity. Methods A total of 36 cases received autologous free fat graft for repair of tear trough deformity from May 2015 to May 2017. Autologous fat granules were obtained by liposuction on the inner side of thigh root and they were purified by repeated static and rinsing. After that, homogeneous and pure autologous fat granules were obtained by filtering fibrous tissue with double-layer medical gauze. The autologous fat granules were injected into the subcutaneous layer and the upper periosteum in depression of tear trough, and the upper periosteum was filled with excess 10% to 20% injection. Results All cases were followed up for 6 to 12 months. There were 33 cases achieved satisfactory results for first-time filler injection and 3 cases achieved satisfactory results after a second-time filler injection. There were no complications such as infection, liquefaction, hematoma, pigmentation and sclerosis after operation. The tear trough deformity was improved obviously with natural outline, and the effect was satisfactory. Six months after operation, the repair effect was compared with that before operation and evaluated. The patient satisfaction rate was 91. 7%, and the doctor satisfaction rate was 94. 4%. Conclusion Autologous free fat graft has less injury, faster recovery and fewer complications in repair of tear trough deformity. The effect of stratified injection is satisfactory.