Abstract:Objective To investigate the clinical effect of Wenshen Huatan Quyu prescription combined high-intensity focused ultrasound in the treatment of uterine fibroid. Methods A total of 94 uterine fibroid patients who received treatment from February 2016 to June 2017 were selected and divided into observation group and control group randomly (47 cases each). The control group patients received high-intensity focused ultrasound, and the observation group patients received Wenshen Huatan Quyu prescription combined high-intensity focused ultrasound. The levels of sex hormones and hemorheology were measured before and after treatment in two groups. B-ultrasonography was used to detect the volume change of myoma and uterus. Results The total efficacy rate in observation group was significant higher than that in control group (91.49% vs 72.34%, P<0.05). After treatment, estrogen, progesterone, follicle stimulating hormone and luteinizing hormone in the observation group were decreased significantly, and they were significant lower than those in the control group (all P<0.05). After treatment, the blood viscosity of the observation group, the low and high shear viscosity of the whole blood and the specific volume of blood cells decreased significantly, and they were significantly lower than those of control group(all P<0.05). The volume of myoma and uterus were decreased after the treatment in both groups(all P<0.05). And the volume of myoma and uterus in observation group were less than those in control group after the treatment [(24.54±5.31)cm³ vs (30.01±6.27)cm³, (92.37±9.08)cm³ vs (101.43±10.22)cm³, all P<0.05]. Conclusion Wenshen Huatan Quyu prescription combined high-intensity focused ultrasound has a reliable curative effect in the treatment of uterine fibroid, which could improve the level of sex hormones and hemorheology.