Abstract:Objective To explore the application of enteral nutrition support nursing and its influences on immune function and wound recovery in patients with extensive severe burn. Methods The clinical data of 200 patients with extensive severe burns in the First Affiliated Hospital of Hebei North University from January 2019 to September 2020 were retrospectively analyzed. Among them, 98 cases who were given parenteral nutrition support were included in group B, while other 102 cases who were given enteral nutrition support nursing were included in group A. The wound recovery, nutritional status ［subjective global assessment (SGA), short-form mini-nutritional assessment (MNA-SF)］, gastrointestinal function, psychological state ［acceptance of disability scale (ADS)］, quality of life ［Chinese version of the Brief Burn Specific Health Scale (BSHS-B)］ and occurrence of adverse reactions were compared between the two groups. Results The wound recovery time in group A was shorter than that in group B (P＜0.05). SGA score in group A was lower than that in group B ［(12.91±2.06) points vs (14.36±2.11) points］, while MNA-SF score was higher than that in group B ［(11.29±1.04) points vs (9.88±1.50) points］ (P＜0.05). At 7d and 14d after admission, levels of serum gastrin and plasma motilin in group A were higher than those in group B. ADS score in group A was lower than that in group B ［(61.36±3.55) points vs (69.98±3.49) points, P＜0.05］, while BSHS-B score was higher than that in group B ［(128.65±9.82) points vs (119.68±9.44) points, P＜0.05］. There was no significant difference in incidence of adverse reactions between the two groups (P＞0.05). Conclusion Enteral nutrition support nursing can promote wound healing in patients with extensive severe burns, accelerate the recovery of gastrointestinal function, enhance nutrition, improve psychological state and quality of life.