Abstract:Cardiomyopathy is a heart disease clinically characterized by enlargement of the heart, arrhythmia and heart failure alone or simultaneously. Ischemic cardiomyopathy is usually caused by coronary atherosclerotic lesions, but non-ischemic cardiomyopathy (NICM) is different. It is caused by non-coronary atherosclerotic lesions which can cause heart failure, arrhythmia, and even sudden death. However, the pathogeny, diagnosis and treatment methods of NICM are still unclear, and the efficacy needs to be explored further. The article analyzes the pathogeny, diagnosis, current status of drugs and non-drug treatment of NICM, aiming to provide more reference materials for the early prevention of patients with NICM and provide direction for the diagnosis and treatment of NICM.