本文已被：浏览 167次 下载 211次
投稿时间：2023-12-29 网络发布日期：2024-05-20
投稿时间：2023-12-29 网络发布日期：2024-05-20
中文摘要: 目的 探讨自体富血小板血浆（PRP）椎间盘内注射对椎间盘源性腰痛（DLBP）的治疗效果。 方法 回顾性分析2022年1月至2023年6月于联勤保障部队第九〇八医院就诊的47例DLBP患者的临床资料。根据治疗方法分为PRP联合塞来昔布胶囊治疗组（试验组）16例和单纯塞来昔布胶囊治疗组（对照组）31例。统计治疗前、治疗后1周、治疗后1个月及6个月的腰痛视觉模拟评分（VAS）及Oswestry功能障碍指数（ODI）。结果 随着治疗时间的推移，试验组VAS、ODI评分逐渐降低；对照组治疗后1周的VAS、ODI评分较治疗前降低，之后呈现逐渐上升趋势；试验组治疗后1个月、治疗后6个月VAS评分及ODI评分低于对照组（P＜0.05）。 结论 自体PRP联合塞来昔布胶囊治疗DLBP远期疗效要优于单纯口服塞来昔布胶囊，可作为DLBP的一种有效治疗方式。
Abstract:Objective To investigate the efficacy of intradiscal injection of autologous platelet-rich plasma (PRP) in the treatment of discogenic low back pain (DLBP). b>Methods A retrospective analysis of clinical data from 47 DLBP patients treated at No.908 Hospital of Joint Logistics Support Force from January 2022 to June 2023 was conducted. Patients were divided into a PRP combined with celecoxib capsule treatment group (experimental group, n=16) and a celecoxib capsule monotherapy group (control group, n=31) based on the treatment method. The visual analogue scale (VAS) of low back pain and Oswestry disability index (ODI) scores were recorded before treatment, at 1 week, 1 month, and 6 months after treatment.Results VAS scores and ODI scores in the experimental group gradually decreased over time; the VAS scores and ODI scores in the control group decreased at 1 week after treatment compared to before treatment, but then showed a gradual upward trend. The VAS scores and ODI scores in the experimental group were lower than those in the control group at 1 month and 6 months after treatment (P＜0.05).Conclusion he long-term efficacy of autologous PRP combined with celecoxib capsule in treating DLBP is superior to that of celecoxib capsule monotherapy and can be considered as an effective treatment for DLBP.
文章编号： 中图分类号：R681.5 文献标志码：A
基金项目:江西省卫健委科技计划项目（202210458）
引用文本：
帅明,何成,赵岚,等.自体富血小板血浆椎间盘内注射治疗椎间盘源性腰痛的疗效[J].中国临床研究,2024,37(5):735-738.
帅明,何成,赵岚,等.自体富血小板血浆椎间盘内注射治疗椎间盘源性腰痛的疗效[J].中国临床研究,2024,37(5):735-738.