Abstract:Objective To explore the preventive effect of bundle nursing in the prevention of central venous catheter-related bloodstream infections (CRBSI) in critically ill cardiac patients. Methods A total of 200 critically ill cardiac patients who received central venous catheter treatment at The First Affiliated Hospital of Xinjiang Medical University from June 2021 to June 2022 were included as the study subjects. Among them, 100 patients who received routine nursing from June to December 2021 were assigned to the control group, and 100 patients who received bundle nursing from January to June 2022 were assigned to the experimental group. The infection-related indicators, bacterial culture positivity rate, CRBSI rate, duration of catheter placement, and ICU length of stay were compared between two groups. Results The experimental group had a lower proportion of abnormal temperature, white blood cell count, procalcitonin, C-reactive protein, and other indicators before extubation compared to the control group. Compared with control group, experimental group had a lower bacterial culture positivity rate ［20.00% (5/25) vs 45.95% (17/37), χ²=4.387, P=0.036］ and infection rate (5.00% vs 17.00%, χ²=7.354, P＜0.01), and the duration of catheter placement and length of ICU stay were shorter in the experimental group (P＜0.05). Conclusion Bundle nursing intervention in critically ill cardiac patients who have undergone central venous catheter treatment can reduce the incidence of CRBSI.