Abstract:Objective To explore the application effect of healthcare failure mode and effect analysis(HFMEA) in the risk management of intraoperative acquired pressure injury(IAPI) in neurosurgery patients. Methods A total of 160 surgical patients admitted to the Second Affiliated Hospital of Air Force Medical University from March to August 2022 were selected by convenience sampling method as the research subjects. Patients from March to May were set as control group, and those from June to August were set as experimental group. Thirty-two operating room nurses were also included. The traditional process was used to prevent IAPI during operation in control group, and a multidisciplinary management team for stress injury was established on the basis of the control group in experimental group. The HFMEA mode were used to analyze the failure reasons of the process steps, and to formulate and implement the intervention plan. The incidence of high-risk failure link and IAPI ,and the professional ability of operating room nurses in preventing IAPI were compared before and after implementation. Results After the implementation of HFMEA, the incidence of high-risk failure mode decreased from 16.92% to 2.55%, and the incidence of IAPI decreased from 7.9% to 0,while the scores of nurses' theoretical examination increased from (84.09 ±3.48 ) to (92.97±3.32) and operation examination increased from (85.06±2.90) to (92.28±3.08) , yielding statistically significant differences (P＜0.05). Conclusion The application of HFMEA can optimize the IAPI management process of neurosurgical patients, standardize the behavior of nursing staff, and thus improve the quality of nursing.