Abstract:Objective To explore the influencing factors and countermeasures of chemotherapy compliance in leukemia patients complicated with diabetes. Methods A total of 164 leukemia patients with diabetes admitted to Hematology Department of West China Hospital between May 2017 and November 2021 were enrolled as the research subjects. After collecting the general data of patients, the patients were divided into good compliance group（n=113） and poor compliance group（n=51） according to the evaluation by Morisky medication adherence scale during chemotherapy. The influencing factors of chemotherapy compliance were analyzed by univariate analysis, and the risk factors influencing compliance differences were analyzed by logistic regression method. Results There were significant differences in comparison of education level, residence, personal monthly income, marital status, knowledge level of disease and chemotherapy, adverse reactions after medication and emotional stability between poor compliance group and good compliance group（P<0.05）. Logistic regression analysis showed that personal monthly income of less than 4000 yuan（OR=2.962）, unmarried or widowed （OR=2.869）, adverse reactions after medication（OR=2.713） and emotional instability（OR=2.617） were the independent risk factors of poor chemotherapy compliance（P<0.05）. ConclusionMedical staffs should focus on the patients with low income, marital status of unmarried or widowed, adverse reactions after medication and emotional instability and provide timely intervention through diet, health education, and psychological nursing.