Abstract:ObjectiveTo strengthen the whole process management of intravenous chemotherapy administration to ensure the safety of patients and nurses. MethodsThe healthcare failure mode and effect analysis（HFMEA） was used to analyze the failure mode in the process of intravenous chemotherapy administration, and risk scoring matrix and decision tree were used to find out what should be improved. Based on the established improvement measures, the intelligent module for safe administration of intravenous chemotherapy was designed and embedded in the mobile nursing information system for application in the clinical. ResultsAfter the application of intelligent module, the correct rates of chemotherapy drug configuration（100.00% vs96.45%）, the chemotherapy infusion（98.92% vs94.29%） and the chemotherapy occupational protection（99.65% vs97.28%） statistically increased compared with those before application of intelligent module（P＜0.05, P＜0.01）. ConclusionThe intelligent module for intravenous chemotherapy safe medication can standardize the chemotherapy process, improve the quality of chemotherapy nursing and ensure the safety of patients and nurses.