Abstract:Objective To investigate the predictive factors of acute cerebral infarction in patients with stable chronic obstructive pulmonary disease (COPD).Methods From January 2016 to December 2020, 60 patients with acute cerebral infarction in stable COPD in Huai'an First People's Hospital were selected as the case group, and 90 patients without acute cerebral infarction in stable COPD in the same period were selected as the control group. The basic clinical data of the two groups and the related laboratory indicators of venous blood within 24 hours after admission were collected and statistically analyzed. Results There were significant differences between the two groups in age, history of diabetes, smoking history, white blood cells count, red blood cell distribution width (RDW), monocytes count, prothrombin time, red blood cell count, hemoglobin, hematocrit and mean hemoglobin concentration of red blood cells (P<0.05, P<0.01). Logistic regression analysis showed that RDW, monocytes count and history of diabetes were correlated with the occurrence of cerebral infarction in patients with stable COPD. The areas under ROC of the three factors were 0.770, 0.607 and 0.575, respectively. The sensitivity was 63.3%, 58.3% and 21.7% respectively, and the specificity was 80.0%, 58.9% and 93.3% respectively. Conclusion Among many predictive factors in this study, RDW has the highest predictive value for acute cerebral infarction in patients with stable COPD, which provides a certain clinical basis for early identification and early intervention of such patients.