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中国临床研究:2022,35(8):1134-1137
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脑小血管病与静脉溶栓治疗急性缺血性脑卒中的相关性研究进展
(1. 徐州市中心医院神经内科,江苏 徐州 221009;2. 南京中医药大学研究生院,江苏 南京 210023;3. 徐州医科大学徐州临床学院,江苏 徐州 221004)
Research progress of correlation between cerebral small vessel disease and intravenous thrombolysis for acute ischemic stroke
摘要
本文已被:浏览 476次   下载 312
   网络发布日期:2022-08-20
中文摘要: 静脉溶栓对于发病时间窗内急性缺血性脑卒中(AIS)患者是公认的有效治疗手段。神经影像技术的进步使越来越多的AIS患者检测出合并有脑小血管病。相关研究表明脑小血管病会增加AIS静脉溶栓出血转化发生风险和转归不良,但目前结论尚未统一。本文从脑小血管病亚型和脑小血管病总体负荷两个角度出发,综述其对AIS静脉溶栓出血转化和临床转归影响的研究进展。
Abstract:Intravenous thrombolysis is an effective treatment for patients with acute ischemic stroke (AIS) within the onset time window. With the development of neuroimaging technology, the detection rate of cerebral small vessel disease(CSVD)is higher in AIS patients. Related studies have shown that CSVD can increase the risk and poor outcome of hemorrhage following thrombolytic therapy for AIS, but there has not yet been a unified conclusion at present.Focusing on the subtypes of CSVD and the total illness burden, this paper reviews the research progress of hemorrhage transformation and clinical prognosis in AIS patients after intravenous thrombolysis.
文章编号:     中图分类号:R743.3    文献标志码:A
基金项目:国家重点研发计划精准医学研究(2016YFC0901004)
引用文本:
陈彤,陈国芳,陈政宇,等.脑小血管病与静脉溶栓治疗急性缺血性脑卒中的相关性研究进展[J].中国临床研究,2022,35(8):1134-1137.

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