Abstract:Objective To investigate the efficacy and related complications of nasojejunal tube (NJT) feeding and jejunostomy tube (JT) feeding after pancreaticoduodenectomy (PD). Methods A retrospective analysis was performed on 102 patients who received PD at Nanjing Drum Tower Hospital from January 2014 to December 2017. According to different feeding methods, the patients were divided into NJT group (n=51) and JT group (n=51). The incidences of postoperative complications and catheter-related complications and the feeding tube efficiency indicators were compared between two groups. Results There was no significant difference in pancreatic texture, pancreatic duct diameter, intraoperative bleeding, American Society of Anesthesiologists (ASA) score, anesthesia risk evaluation score, grade of complication, incidences of secondary operation, pancreatic fistula, infectious complications, gastrointestinal bleeding, abdominal bleeding, hyperglycemia and intestinal related complications between two groups (P>0.05). The readmission rate, the incidences of intestinal obstruction, delayed gastric emptying and nutritional tube-related complications in NJT group were lower than those in JT group, and the time of removing nasogastric tube, the time of transition to oral feeding and the time of removing nutrition tube were shorter than those in JT group (P<0.05,P<0.01). Conclusion NJT feeding after PD is safer and has fewer complications compared with JT. It can significantly reduce the incidence of gastric emptying disorder and shorten the postoperative hospital stay.