Abstract:Objective To explore the effects of integrated management and comprehensive geriatric assessment (CGA) nursing model on psychological factors and quality of life of patients with prostate cancer. Methods A total of ninety-six patients diagnosed with prostate cancer and underwent laparoscopic radical prostatectomy(LRP) for the first time in Nanjing First Hospital from March 2020 to March 2021 were selected and randomly divided into control group, observation group 1 and observation group 2(n=32, each). The routine nursing mode was given after admissionin in control group,CGA intervention was performed in observation group 1, and CGA intervention with integrated management was performed in observation group 2. All patients were evaluated by self-rating anxiety scale (SAS) and self-rating depression scale (SDS) before intervention and at discharge, and evaluated by core quality of life questionnaire QLQ-C30 (V3.0) and prostate cancer-specific module supplementary scale (QLQ-PR25)before intervention and 30 days after operation. Results SAS and SDS scores in observation group 2 were significantly better than those in control group and observation group 1 at discharge(P<0.05). At 30 days after operation, the QLQ-C30 and QLQ-PR25 scores of quality of life in observation group 2 were obviously better than those in control group and observation group 1 (P<0.05). Conclusion The integrated management and CGA nursing model can effectively improve the psychological state and postoperative quality of life for patients with prostate cancer.