Abstract:ObjectiveTo investigate the effect of abnormal working time on door-to-balloon time(D2B) in acute ST-segment elevation myocardial infarction(ASTEMI) patients.Methods A retrospective analysis was performed on 120 ASTEMI patients who received primary percutaneous coronary intervention(PPCI) from January 1,2018 to December 31,2019.According to the actual time of visit,the patients were divided into the normal working time group (41 cases) and the abnormal working time group (79 cases).The baseline data and D2B time were compared between the two groups,and the related factors of D2B delay (D2B≥90 min) were analyzed by Logistic multivariate regression analysis.Results The D2B time ［85.0(72.0±97.0)min vs 60.0(44.0±82.0)min,P<0.01 ］ and the incidence of D2B time ≥ 90 min (41.8% vs12.2%,P<0.01 ) in abnormal working time group were higher than those in normal working time group.Confirmation-catheter room start-up time,informed consent time,catheter room start-up-catheter room activation time and catheter room [JP2]activation-patient entry time in abnormal working time group were longer than those in normal working time group (P<0.05 ,P<0.01 ).Logistic multivariate regression analysis showed that abnormal working time was one of the factors [JP2]affecting D2B time［OR=17.445,95%CI(1.337-227.589),P=0.029］.Conclusion Abnormal working time is one of the factors that affect the D2B time,which is mainly reflected in the delay of the start-up of the catheter room,whether the [JP2]delay of doctors′ decision-making and informed are statistically significant needs to be further observed by expanding the sample size.