Abstract:Objective To study the main clinical features and causes of death of patients with coronavirus disease 2019 (COVID-19). Methods A retrospective analysis was performed on the general information,laboratory examination results and treatment of 9 deaths among 197 patients with confirmed COVID-19 from January 30 to February 20,2020 in the Central Theater Command General Hospital of PLA. Results All the 9 patients died of critical diseases,including 7 males and 2 females with average age of (82.1±12.4) years,and 6 patients were complicated with more than two basic diseases.In most patients at admission,the levels of fasting blood glucose (FPG),C-reactive protein (CRP),interleukin-6 (IL-6),aspartate aminotransferase (AST) and urea nitrogen (BUN) were higher than normal levels,while oxygen saturation,partial pressure of oxygen,partial pressure of carbon dioxide,lymphocyte count,total T lymphocyte absolute number,inhibitory/cytotoxic T lymphocyte absolute number and helper T lymphocyte absolute number were lower than normal.Among 9 patients,7 died of respiratory failure caused by critical COVID-19,1 died of acute pulmonary embolism,and 1 died of cardiac arrest;there were 6 cases complicated with multiple organ failure syndrome,with secondary infection in 3 cases and shock in 3 cases. ConclusionFor the patients with critical COVID-19,the survival rate of elderly male patients with multiple underlying diseases is low,and close monitoring of blood gas analysis,blood glucose,blood routine,T lymphocyte typing,inflammation indicators,liver and kidney function can help to predict the development and prognosis of patients.