Abstract:Objective To investigate the risk factors of recurrent respiratory tract infections (RRTIs) in children and the correlation between vitamin A,vitamin D and vitamin E and RRTIs. Methods A total of 174 children with RRTIs in Tangshan Union Medical College Hospital from September 2018 to September 2019 were selected as observation group.According to the principle of 1[DK]∶1 matched case-control study,174 children undergoing physical examination were selected as control group at the same time.Univariate and multivariate Logistic analysis were performed on the general demographic data and blood test results to study the risk factors of RRTIs. Results Logistic regression analysis showed that outdoor activities for more than 2 hours (OR=0.244,95% CI:0.116-0.514),suitable vitamin A (OR=0.098,95% CI:0.047-0.206),suitable vitamin D (OR=0.360,95% CI:0.143-0.903),suitable vitamin E (OR=0.390,95% CI:0.191-0.797) were the preventing factors of RRTIs in children (all P<0.05).Antibiotic abuse (OR=4.533,95% CI:2.385-8.615) was the risk factor of RRTIs in children (P<0.05). Conclusion The incidence rate of RRTIs in children can be reduced by adequate intake of vitamin A,vitamin D and vitamin E,outdoor activity for more than 2 h per day and avoiding abuse of antibiotics.