Abstract:Objective To assess the correlation between computed tomography enterography (CTE) and clinical features of Crohn′s disease. Methods The CTE data from 60 patients with Crohn′s disease from September 2016 to September 2019 were collected.And the clinical parameters were retrospectively analyzed.The CTE parameters include:thickening and strengthening of the intestinal wall,mesenteric fatty hyperplasia,increased blood vessels and complications (fistula,stenosis,abscess).The disease activity of Crohn′s disease was assessed by Crohn′s disease activity index (CDAI) and clinical biochemical markers (C-reactive protein,erythrocyte sedimentation rate,platelets,hemoglobin).Multiple linear regression was used to analyze the correlation between CTE parameters,clinical activity index and laboratory parameters. Results The increased CDAI was significantly related to fat density (P=0.03),intestinal stenosis (P=0.04),and pectinopathy (P=0.01).Increased ESR was associated with enlarged mesenteric lymph nodes (P=0.04) and mucosal enhancement (P=0.01). Conclusion Crohn′s disease patients with peri-intestinal inflammation (increased fat density) manifestations and pectinopathy with CTE are clinically active and require more aggressive treatment.