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投稿时间：2020-05-20 网络发布日期：2021-02-20
投稿时间：2020-05-20 网络发布日期：2021-02-20
中文摘要: 目的 探讨手法复位石膏外固定术联合口服盘龙七片治疗A3型桡骨远端骨折的早期疗效,为临床治疗提供参考。方法 选取2018年6月至2020年1月于邳州医院治疗的A3型桡骨远端骨折患者100例，随机分为对照组(手法复位石膏外固定术,50例)和研究组(手法复位石膏外固定术联合口服盘龙七片,50例)。比较两组患者治疗前和治疗7 d血清IL-1、IL-6、TNF-α水平及治疗后4周Gartland-Werley腕关节评分,评价两组患者早期临床治疗效果。结果 经过7 d治疗后,两组血清IL-1、IL-6、TNF-α水平均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05,P<0.01)。研究组患者拆除石膏后Gartland-Werley腕关节评分优良率高于对照组,差异有统计学意义(82.0% vs 48.0%,χ2=12.703,P<0.01)。结论 手法复位石膏外固定术联合口服盘龙七片治疗A3型桡骨远端骨折,较之单纯手法复位石膏外固定能有效降低骨折炎性反应,缓解疼痛、肿胀。
Abstract:Objective To study the early curative effect of manipulative reduction and plaster external fixation combined with Panlongqi tablet on type A3 distal radius fracture.Methods A total of 100 patients with A3 type distal radius fractures treated between June 2018 and January 2020 were selected and randomly divided into control group ( n=50,treated with manipulative reduction and external fixation) and study group ( n=50,treated with manipulative reduction and external fixation combined with Panlongqi tablet).The serum levels of IL-1,IL-6 and TNF-α before and 7 days after treatment and the Gartland-Werley wrist (GW) score at 4 weeks after treatment were compared between two groups to evaluate the early effect of treatment.Results After 7 days of treatment,the levels of serum IL-1,IL-6 and TNF-α were significantly lower than those before treatment in two groups,and they were statistically lower in study group than those in control group ( P<0.05, P<0.01).In GW score,the excellent and good rate in study group was significantly higher than that in control group (82.0% vs 48.0%, χ2=12.703, P<0.01).Conclusion In the treatment of patients with type A3 distal radius fractures,manipulative reduction and external fixation combined with oral Panlongqi tablet can effectively reduce postoperative inflammatory reactions,relieve pain and swelling.
keywords: Type A3 distal radius fracture Manipulative reduction Plaster external fixation Panlongqi tablet Inflammatory factor Gartland-Werley wrist scores
文章编号： 中图分类号：R683.4 文献标志码：B
基金项目:中国博士后科学基金(2020M681739)；江苏省重点实验室开放课题资助项目(XZSYSKF2020004,XZSYSKF2020028)；徐州医科大学校级科研资金(2018KJ23)[ZK)]
附件
| 作者 | 单位 |
| 戴成柏1 | 1.徐州医科大学附属邳州医院骨科,江苏 徐州 221300； |
| 李剑1 | 1.徐州医科大学附属邳州医院骨科,江苏 徐州 221300； |
| 邵礼武1 | 1.徐州医科大学附属邳州医院骨科,江苏 徐州 221300； |
| 耿庆贺1,2 | 1.徐州医科大学附属邳州医院骨科,江苏 徐州 221300；2.徐州医科大学肿瘤研究所,江苏 徐州 221300 |
| Author Name | Affiliation |
| DAI Cheng-bai*,LI Jian,SHAO Li-wu,GENG Qing-he | *Department of Orthopeadic,Pizhou Hospital of Xuzhou Medical University,Xuzhou,Jiangsu 221300,China |
引用文本：
戴成柏,李剑,邵礼武,等.手法复位石膏外固定联合盘龙七片治疗A3型桡骨远端骨折的早期疗效[J].中国临床研究,2021,34(2):190-192.
戴成柏,李剑,邵礼武,等.手法复位石膏外固定联合盘龙七片治疗A3型桡骨远端骨折的早期疗效[J].中国临床研究,2021,34(2):190-192.