Abstract:Objective To explore the effects of progressive muscle relaxation training(PMRT) on improving the anxiety,depression and sleep quality of patients with coronavirus disease 2019 (COVID-19). Methods A total of 93 patients in the COVID-19 isolation ward of grade-A tertiary hospital in Wuhan from February to March 2020 were selected as the research subjects,including 47 cases in the intervention group and 46 cases in the control group.Based on the routine treatment and nursing in two group,PMRT was performed in intervention group.PSQI,PHQ-9,and GAD-7 were used for patients′ evaluation at admission,discharge and after isolation. Results The differences in the inter-group-effect and time-effect of the PHQ-9 and GAD-7 scores between the two groups of patients were statistically significant (P＜0.05,P＜0.01),and there were interaction-effect between intervention factor and time factor(P＜0.05,P＜0.01).The differences in the inter-group-effect of PSQI total score,sleep quality,time to fall asleep,sleep time,sleep efficiency,sleep disturbance,and day dysfunction between the two groups of patients were statistically significant (P<0.05,P<0.01).The differences in the time-effect of PSQI total score,sleep quality,time to fall asleep,sleep time,sleep efficiency,sleep disturbance,hypnotics and day dysfunction between the two groups of patients were statistically significant (all P<0.01).There were interaction-effect between intervention factor and time factor in PSQI total score,sleep quality,time to fall asleep,sleep time and sleep efficiency (P<0.05,P<0.01). Conclusion PMRT can significantly improve the anxiety,depression and sleep quality in patients with COVID-19.