Abstract:Objective To observe the effect of etomidate combined with remifentanil in painless bronchoscopy.Methods 75 patients who underwent painless bronchoscopy at the Respiratory Endoscopy Center from January 2016 to June 2018 were selected as the research objects,and were randomly divided into group A,group B and group C.Patients in group A were given propofol combined with remifentanil;patients in group B were given etomidate combined with remifentanil;patients in group C were given etomidate combined with fentanyl.The mean arterial pressure (MAP) and Blood oxygen saturation (SpO2) of the three groups at each time point ［T0 (before anesthesia),T1(after induction),T2(bronchoscopy through the glottis),T3(end of examination),T4(leave the operating room)］ were recorded.Total anesthetic usage,postoperative recovery time,and adverse reactions were compared.Results The differences of MAP and SpO2 between groups,time and interaction were statistically significant ( P<0.05, P<0.01).Pairwise comparison showed that there was no statistical difference in MAP between the three groups at T0 and T1( P>0.05);There was a statistically significant difference between the three groups at T2,T3,and T4( P<0.01);There was no statistical difference between the three groups of SpO2 at T0,T2,T3 and T4( P>0.05);The comparison between the three groups at T1,the difference was statistically significant ( P<0.05).Compared with group B and group C,group A used more drugs and took longer to wake up.The difference was statistically significant ( P<0.05).The incidence of hypotension in group B was lower than that in group A,and the difference was statistically significant ( P<0.017).ConclusionIn painless bronchoscopy,the administration of etomidate combined with remifentanil for anesthesia can safely and effectively complete the examination and achieve the purpose of rapid recovery.