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投稿时间：2020-01-15 网络发布日期：2020-08-20
投稿时间：2020-01-15 网络发布日期：2020-08-20
中文摘要: 目的 探讨白内障超声乳化术后患者行中药汤剂石决明散联合妥布霉素地塞米松滴眼液的临床效果。方法 选取2018年9月至2019年8月接受白内障超声乳化术的患者60例为研究对象,按照随机数字表法分为对照组和观察组,各30例。对照组单纯给予妥布霉素地塞米松滴眼液治疗,观察组行石决明散联合妥布霉素地塞米松滴眼液进行治疗。比较两组患者在治疗1 d、1周、2周及1个月的眼部症状评分、泪腺分泌量(SIT)、泪膜破裂时间(BUT)、角膜荧光素染色评分(FL)、前房闪辉值及黄斑中心凹厚度。结果 观察组治疗有效率高于对照组,差异有统计学意义(93.33% vs 73.33%,P<0.05)。治疗2周、1个月时,观察组眼部症状评分、前房闪辉值均低于对照组,差异有统计学意义(P<0.05)。治疗1周、2周、1个月时,观察组SIT、BUT均长于对照组,FL评分、黄斑中心凹厚度低于对照组,差异有统计学意义(P<0.05)。两组均无明显不良反应。结论 石决明散联合妥布霉素地塞米松滴眼液可用于白内障的术后恢复,具有非常好的临床效果,且安全性高。
中文关键词: 白内障 白内障超声乳化术 石决明散 妥布霉素地塞米松滴眼液
Abstract:ObjectiveTo explore the method and clinical effect of Chinese medicine decoction shijueming powder combined with tobramycin -dexamethasone eyedrops in the patients after phacoemulsification.MethodsSixty patients with phacoemulsification operation from September 2018 to August 2019 were selected and randomly divided into control group and experimental group(n=30,each).Shijueming powder combined with tobramycin-dexamethasone eyedrops was given in experimental group,and tobramycin-dexamethasone eyedrops alone was used in control group.The eye symptom score,lacrimal gland secretion［SchirmerⅠtest (SIT)］,tear film break-up time (BUT),corneal fluorescein(FL) staining score,anterior chamber flash value and macular fovea thickness were compared between two groups at 1 day,1 week,2 weeks and 1 month after treatment.ResultsThe effective rate in experimental group was significantly higher than that in control group（93.33% vs 73.33%,P<0.05）.At 2 weeks and 1 month after treatment,the eye symptom score and anterior chamber flash value in experimental group were significantly lower than those in control group （P<0.05）.At 1 week,2 weeks and 1 month after treatment,SIT and BUT in experimental group were significantly higher than those in control group,and FL score and macular fovea thickness were statistically lower than those in control group (P<0.05).There was no significant adverse reaction in both groups.ConclusionShijueming powder combined with tobramycin dexamethasone eye drops can be used for the postoperative recovery of patients after cataract with good clinical effect and high safety.
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附件
| Author Name | Affiliation |
| ZHANG Wen-wen,LI Qi-feng | Department of Ophthalmology,Pukou Hospital of Traditional Chinese Medicine,Nanjing,Jiangsu 211800,China |
引用文本：
张文文,李奇峰.中药汤剂石决明散联合妥布霉素地塞米松滴眼液对白内障超声乳化术后恢复的效果[J].中国临床研究,2020,33(8):1108-1110,1114.
张文文,李奇峰.中药汤剂石决明散联合妥布霉素地塞米松滴眼液对白内障超声乳化术后恢复的效果[J].中国临床研究,2020,33(8):1108-1110,1114.