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投稿时间：2020-01-03 网络发布日期：2020-05-20
投稿时间：2020-01-03 网络发布日期：2020-05-20
中文摘要: 目的 调查儿童的总摄氟量,探讨总摄氟量与不同途径氟摄入量的相关关系,为地方性氟中毒防制及效果评价提供依据。方法 选择地方性氟中毒重病区江苏省泗洪县瓦庙村为调查点,该村236名在校2~6年级学生为调查对象,检测儿童家庭的饮水、食物和空气的氟含量,计算每位儿童每天的总摄氟量,统计分析儿童总摄氟量与不同途径摄氟量的相关关系。结果 瓦庙村儿童家庭手压井水氟含量(2.45±0.80)mg/L,煮沸水氟含量(1.87±0.79)mg/L,井水氟含量显著高于煮沸水,差异有统计学意义(t=7.928,P=0.000)。每位儿童经食物的摄氟量为0.61 mg/d。按照总摄氟量的计算公式,该村每位儿童总摄氟量0.73~5.57(3.05±0.99)mg/d。饮水氟是儿童摄氟的主要来源,占80.06%,经Logistic Model进行曲线拟合后,饮水氟含量与总摄氟量的回归方程为y=4.88/(1+8.51×e0.71x)。结论 瓦庙村儿童的总摄氟量显著高于国家标准,饮水氟为儿童的主要摄氟来源,饮水降氟是该村防治地方性氟中毒的主要措施。
Abstract:ObjectiveTo investigate the total fluoride intake (TFI) for each child,to explore the relationships among the TFI and the fluoride intake from different way,and to provide evidences for endemic fluorosis control and the effect assessment.MethodsWamiao village,a severe endemic fluorosis areas,was selected for this study.236 students from grade 2 to grade 6 in the village primary school were recruited for our investigation.Drinking water fluoride in each child′s household shallow wells,fluoride in diet,and fluoride in outdoor or indoor′s air were detected.Then the TFI were calculated according to the national criteria of China.The relationship among the TFI and the fluoride intake from different way were analyzed.ResultsThe level of fluoride in drinking water was higher than that in boiling water in superficial wells in Wamiao village［(2.45±0.80)mg/L vs (1.87±0.79)mg/L,P<0.01］.The level of fluoride in diet was 0.61 mg/d.[JP2]According to the calculation formula of total fluorine uptake,the total fluorine uptake of each child in the village was 0.73-[JP]5.57(3.05±0.99) mg/d.Drinking water fluoride was the main source for Wamiao village′s children,accounting for 80.06%.The regression equation between the drinking water fluoride and the TFI was y=4.88/(1+8.51×e0.71x) according to the Logistic Model.ConclusionThe average TFI in children in Wamiao village is significantly higher than that of the National Criteria,and the fluoride in drinking water is the main source for children.Defluoridation from the drinking water is the main measure for endemic fluorosis prevention in this village.
文章编号： 中图分类号： 文献标志码：B
基金项目:国家自然科学基金(81573101)
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引用文本：
向杰,涂青云,覃玉,等.地方性氟中毒病区儿童总摄氟量调查分析[J].中国临床研究,2020,33(5):690-692，696.
向杰,涂青云,覃玉,等.地方性氟中毒病区儿童总摄氟量调查分析[J].中国临床研究,2020,33(5):690-692，696.