Abstract:ObjectiveTo study the clinical characteristics,serotype distribution and drug resistance in patients with Salmonella enteritis.MethodsA retrospective analysis was made on the clinical characteristics,serotype distribution and drug resistance of pathogenic bacterial in 95 patients with Salmonella enteritis admitted to hospital from April 2016 to October 2018.ResultsThe positive rate of Salmonella was statistically different among the elderly group(≥60 years old),middle-aged group(45-59 years old)and youth group (14-44 years old),and it was significantly higher in the elderly group than that in youth group,and the difference was statistically significant(P<0.017).The symptom incidences were 57.89% of watery stool (stool property),68.42% of fever,47.37% of abdominal pain,44.21% of nausea,14.74% of vomiting,9.47% of tenesmus,and 5.26% of dehydration,respectively in patients. Out of 16 serotypes in 95 Salmonella strains,the dominant serotypes were Salmonella enteritidis and Salmonella typhimurium,accounting for 53.7% and 14.7% respectively.These Salmonella strains were sensitive to ceftriaxone (95.8%) and trimethoprim/sulfamethoxazole (87.4%) and resistant to ampicillin (55.8%) and ampicillin/sulbactam (30.5%).ConclusionsThe elderly are at high risk of Salmonella enteritis,with main clinical manifestations of watery stool,fever,abdominal pain,nausea,etc.The most prevalent serotypes are Salmonella enteritidis and Salmonella typhimurium.Salmonella is high sensitivity to ceftriaxone,trimethoprim/sulfamethoxazole and high resistance to ampicillin,ampicillin/sulbactam.